It was his first victory ever against a player ranked in the top two and it avenged the semi-final loss at the Rio Olympics where Murray went on to win gold and Nishikori settled for bronze.
A leave vote means the future of Britain's financial services industry is now hanging in the balance.
Andy Murray's preparations for the US Open got off to a poor start when the Briton suffered a stunning loss.
Battle-scarred Argentine Juan Martin del Potro clinched his 21st career title with a 6-4, 6-4 win over Kevin Anderson in the Mexican Open final in Acapulco on Sunday.
Indian tennis star Sania Mirza received a confidence booster ahead of the US Open Grand Slam tournament beginning, on Monday, with a doubles title victory at the Connecticut Open with Monica Niculescu of Romania, in New Haven, USA.
Friday is the last day for White House Chief strategist Steve Bannon, a presidential spokesperson said on Friday.
Argentina's Diego Schwartzman ended a two-year wait for his second ATP tour title as he overpowered an exhausted Fernando Verdasco to win the Rio Open 6-2, 6-3 on Sunday.
Sunday's four-set verdict over Roger Federer was the 28-year-old's 200th singles victory in a major tournament, making him only the sixth player to achieve the feat.
Defending champions Leander Paes and Radek Stepanek had to work hard to cross the first round hurdle in the men's doubles even as Sania Mirza advanced in both the mixed and doubles events at the US Open.
Premier League newcomers Watford suffered a League Cup upset in a 1-0 loss at Preston North End while five-times champions Aston Villa overcame plucky Notts County 5-3 after extra-time to reach the third round on Tuesday.
Photos from matches played at the US Open in Flushing Meadows on Sunday
Images from Day 2 of the Australian Open in Melbourne on Tuesday
Indian squash player Dipika Pallikal notched up a stunning victory against former World number one Rachael Grinham of Australia to clinch the Macau Open title on Sunday.
Donald Trump virtually sealed his Republican nomination for the United States presidential polls on Tuesday night after he scored a major win at the Indiana primary and his nearest rival Texas Senator Ted Cruz bowed out of the race.
Argentine football great Diego Maradona said on Wednesday he wants to fight the "mafia" responsible for the corruption scandal that has rocked FIFA, but he stopped short of saying he wants to be the next president of global soccer's governing body.
IMAGES from Day 3 of the US Open in New York on Wednesday.
During the election campaign Trump had said Clinton would be in jail if he won the elections. He now faces the consternation of supporters who took that pledge literally.
'Washington is well aware that the Haqqani group was responsible for terrorist attacks on the Indian diplomatic establishments in Afghanistan.' 'But today US self-interest dictates that Sirajuddin Haqqani's mainstreaming in Afghan political life and a potential elevation eventually to a leadership role at the national level is useful and necessary, since he can deliver peace,' notes Ambassador M K Bhadrakumar.
Here are some of those lucky celebrities who were invited to watch the Ladies Singles Finals.
Congratulating President-elect Donald Trump on his election victory, President Barack Obama said the nation is now "rooting" for his success in uniting and leading the country and pledged to ensure a smooth transition for his successor.
Krishnamoorthi, 43, won the Chicago-area US House of Representatives seat, the 8th Congressional District, vacated by Tammy Duckworth who won Illinois's US Senate seat.
A ruthless Sorana Cirstea took full advantage of Karolina Pliskova's patchy form at the China Open on Thursday, reaching the quarter-finals as she consigned the recently dethroned world number one to a 6-1, 7-5 defeat.
News of all that's transpired on and off the football field
The narrative in America after Donald Trump's victory sounds like the questions and debates that took place in India after May 2014. Were both electoral results all about jobs and economic anxiety? Mihir S Sharma doubts it.
News of all that's transpired on and off the football field.
Roger Federer blamed troubled preparations for his US Open quarter-final exit on Wednesday, saying he had spent most of the time leading up to the year's final Grand Slam worrying about his back instead of focusing on training.
IMAGES from Day 8 of the US Open on Monday
'There is no meritocracy or at least there is none that is visible and transparent.' 'The Congress has two opportunities to change this,' says Aakar Patel.
The 24-year-old started brightly by taking the first set off the 19th seed on Monday but his lack of match fitness told as, despite frequent treatment from the trainer, he lost the next three to bow out at the first hurdle in a third straight grand slam.
Rediff.com takes a look at some interesting highlights of the tournament.
'Should the Congress take Jyotiraditya's departure as good riddance?', asks Mohammad Sajjad.
Sunil Narine hammered a quickfire half-century as Kolkata Knight Riders outclassed Royal Challengers Bangalore by four wickets at the Eden Gardens in Kolkata.
Bernie Sanders on Sunday trounced Hillary Clinton in the crucial presidential caucuses in Washington, Alaska and Hawaii, making "inroads" into her substantial lead.
Alexandr Kogan, the Cambridge University researcher who developed the app used by Cambridge Analytica, claimed he has been made a scapegoat.
Clinton has blamed her presidential election loss on the "unprecedented" events of Russian cyber hacking and the Federal Bureau of Investigation's probe into her use of her personal e-mail server.
In a historic ruling, the US Supreme Court on Friday legalised same sex marriage, holding that gay people can get married in all 50 states of the country.
How far investors will be convinced by Modi's promise to replace red tape with a "red carpet" remains to be seen.
India's Leander Paes and Sania Mirza made it to the second round of the US Open with straight sets win in their respective doubles events, in New York, on Thursday night.
Pakistan government is holding internal discussions on formulating a policy to deal with the new Indian government under Narendra Modi.
U.S. Open champion Marin Cilic is a firm believer in the new International Premier Tennis League (IPTL), insisting the four-city mixed team tournament is a perfect addition to his preparations for the new season.